FRS 001O - Sec. 001 - (1 unit) - CRN 75087 - W 5:15 – 6:30 pm - 2005 Plant Env. Sci. (PES)

Defense Against Dark Information: Microbes, Microcode and Memes

Instructor: R. Ford Denison, Department of Agronomy & Range Science, College of Agricultural & Environmental Sciences

Description: This seminar will explore possible responses to the risks associated with self-replicating information coded in DNA, computer code, or human language. Bacteria that live inside animals and plants can provide them with vital nutrients or other benefits. But a small change in their genetic programming (natural or deliberate) can cause them to manipulate or kill their hosts. "Bugs" in computer software controlling civilian infrastructure (air traffic control or the power grid) or military weapons systems can have disastrous consequences. Email and cell phones spread infectious ideas, sometimes known as "memes", faster than ever, in ways that may either promote or threaten democracy. Readings and discussion will consider a number of examples of rampaging replicators, looking for unifying principles. Some aspects of modern evolutionary theory will be included, particularly those useful in predicting the rate and direction of evolutionary change in microorganisms (and perhaps computer viruses and rumors). Individual and societal defenses and consequences for civil liberties will be considered. The primary goal of the seminar is to improve students' ability to deal with complex issues where "getting the facts" is necessary but not sufficient. For example, even if experts agree on what the risks and benefits of mass vaccination programs are, they may disagree on whether the benefits exceed the risks. Reasonable people may argue about whether increased surveillance of Americans by the FBI (supposedly, to prevent bioterrorism or malicious use of computer viruses) protects us or threatens us. Students will be encouraged to argue for their point of view in ways that respect differing viewpoints of others. Students will also get practice evaluating and using a variety of information sources, from peer-reviewed journals to the web, and in distinguishing facts, hypotheses, and scientific theories. Significant technical expertise (e.g., in microbiology or computer science) is not a goal. It is hoped that the seminar will stimulate students to explore topics outside of their chosen majors (through classes or additional reading) during their subsequent time at Davis.

Format: The course will informed discussion by students of controversial issues raised by weekly reading assignments of about 20 pages per week. Much of the reading will be excerpts from books (probably including The Selfish Gene; Guns Germs and Steel; Evolution of Infectious Disease; Smart Mobs; Disappearing Cryptography; Hacking Exposed; and Bowling Alone), of which Tide Turners (a novel about a conspiracy to solve the "population problem" by releasing a virus engineered to reduce human fertility) will probably be the most controversial. I will also assign some peer-reviewed journal articles, with the stated expectation that most students will only read the Abstracts. Grading: The course grade will be based on (20%) weekly short quizzes (major points from assigned reading), (40%) class discussion (especially constructive criticism of opposing views), (20%) library/web assignment (1 peer-reviewed article & 1 web article on relevant topic), and (20%) short paper using above sources.

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